What Are Pseudogenes?

Pseudogenes are genomic DNA sequences similar to normal genes but are not expressed into functional proteins; they are regarded as defunct relatives of functional genes. Click here for more background information on pseudogenes and here for a list of our publications on the subject.

Pseudogene Databases

Click here to search through eukaryotic pseudogenes.
Click here to search through prokaryotic pseudogenes.
(Also available: beta-version of a new search interface for Human, Mouse and Worm pgene databases.)

Pseudogene Pipeline

Download the pipeline codes as a compressed file pgplclassic.tgz
View the pipeline README and codes online.

PSEUDOGENE FAMILIES

VIEW PSEUDOGENE FAMILIES starting from GENOMES
VIEW PSEUDOGENE FAMILIES starting from PROTEIN FAMILIES

Human (Homo sapiens)

Mouse (Mus musculus)

Zhang et al. TIG (2004)

Worm (Caenorhabditis elegans)

Harrison et al. NAR (2001), 2001

Fly (Drosophila melanogaster)

Harrison et al. NAR (2003)

Yeast (Saccharomyces cerevisiae)

Cress (Arabidopsis thaliana)

Prokaryotes

Pseudogene assignments for an assortment of prokaryotic genomes are available here.

Cross-genome surveys

Pseudomotifs - PROSITE patterns identified in intergenic regions.
Composition analysis - interactive plots of amino-acid and nucleotide composition data for a variety of organisms, including pseudogenes for worm, fly, human and yeast.