Welcome to PsiDr - The Pseudogene Decoration Resource. The site is developed and maintained by Yale Gerstein Group. It contains a comprehensive knowledgebase of identified pseudogenes, various publication data sets and the pseudogene decoration resource file (psiDR).
In the pseudogene decoration resource file we collected and organized in a consistent manner the large variety of genomic information related to each pseudogene, such as transcriptional activity, chromatin features, functional genomics and evolutionary constraint. Illumina Human BodyMap 2.0 project data, functional genomics data for ENCODE tier 1 and tier 2 cell lines (GM12878, K562, H1-hesc, HeLa-S3 and HepG2) and experimental data were used to create (psiDR). Various models and filters were applied to the corresponding data to predict biological features of pseudogenes. At the end, a list of quantifiers was assigned to each pseudogene according to the model output, such as whether a pseudogene is transcribed, has an active chromatin state or associates with active promoter regions. Tissue/cell line specific information is recorded wherever applicable.